The Big Bang Theory “The Vacation Solution” Season 5 Episode 16 February 9, 2012 News, The Big Bang Theory The Big Bang Theory “The Vacation Solution” Season 5 Episode 16 airs Thursday February 9 (8:00-8:31 PM, ET/PT) on the CBS Television Network. Episode Synopsis: When Sheldon is forced to take his vacation, he goes to work with Amy in her neurobiology lab. Meanwhile, Bernadette wants Howard to sign a pre-nup, on THE BIG BANG THEORY, Thursday, Feb. 9 (8:00 – 8:31 PM, ET/PT) on the CBS Television Network. Show Summary: Leonard and Sheldon are brilliant physicists – wizards in the laboratory, but socially inept outside of it. Enter beautiful, free-spirited neighbor, Penny, who aims to teach them a thing or two about life. While Leonard spends his days looking for love, Sheldon is quite content video-chatting with platonic partner Amy Farrah Fowler, or playing Star Trek 3D Chess with their ever-expanding universe of friends, including fellow scientists Koothrappali and Wolowitz, and Wolowitz’ fiancée, the adorable microbiologist, Bernadette.